Sunday, 23 May 2021 06:44

Debulking Advanced Cancer Larynx in the Patients with Laryngeal Obstruction Featured

Rate this item
(0 votes)

Original Research:

Ali Obaid Muthanna



Background: Debulking advanced cancer larynx in the patients with laryngeal obstruction is an important health issue.

Aim: This study aimed to assess the efficiency of advanced cancer larynx debulking in patients with airway obstruction.

Methods This prospective study was carried out in Oto-Rhinolaryngology Department, Al-Thawra Modern General Teaching Hospital, Sana'a, Yemen, in the period between January 2014 and March 2019. This study included 52 patients with advanced cancer larynx presenting with airway compromise. Debulking of cancer had done to secure the airway.

Results: The mean age of the patients was 57 years. High incidence of cancer larynx in the age group 46-55 (36.5%). The successful rate of debulking was (92.3%), Tracheotomy had done in (7.7%). Presenting symptoms, change of voice, difficulty breathing, stridor, cough, and dysphagia.

Conclusion: Debulking of cancer larynx is a safe and effective alternative to tracheotomy in selected patients in securing the airway in cases with laryngeal cancer to avoid tracheotomy.

Keywords: Airway Obstruction, Debulking, Laryngeal Cancer, Tracheotomy, Yemen


Ali Obaid Muthanna*1

1Department of Otorhinolaryngology, Faculty of Medicine of Health Sciences, Sana'a University, Sana'a, Yemen



  1. Bradley PJ. Treatment of the patients with upper airway obstruction caused by cancer of the larynx. Otolaryngol Head Neck Surg 1999; 120(5): 737-41.

  2. Laccourreye O, Lawson G, Muscatello L, Biacabe B, Laccoureve L, Brasnu D. Carbon dioxide laser debulking for obstructing endolaryngeal carcinoma: a 10-year experience. Ann Otorhinolaryngol. 1999;108(5): 490-4.

  3. Pateri V, Stafford FW, Sammut MS. Laser debulking in malignant upper airway obstruction. Head Neck. 2005;27(4): 296-301.

  4. Gul F, Teleke YC, Yalciner G, Babademez MA. Debulking obstructing laryngeal cancers to avoid tracheotomy.Barz J Otolaryngol. 2019;87 (1): 74-9. Doi.10.1o16 /j.bjor. 2019.7.004PMD: 31540868.

  5. Semoni P, Peters GE, Magnuson JS, Carroll WR. Used of endoscopic debrider in the management of airway obstruction from laryngotracheal carcinoma. Ann Otorhinolaryngol. 2003;112(1): 11-13.

  6. Smith LP, Roy S. Operating room fires in otolaryngology: risk factors and prevention. Am J OtoLaryngol. 2011;32(2): 109-14.

  7. Roy S, Smith LP. Device related risk of fire in oropharyngeal surgery: A mechanical model. Am J Otolaryngol. 2010; Sep 3(5): 356-9.

  8. Matt BH, Cottee LA. Reducing risk of fire in the operating room using Coblation technology. OtoLaryngol 2 010;143(3): 454-5.

  9. Langerman A, Patel RM, Cohen EW, Blair EA, Stenson KM. Airway management before chemoradiation for advanced head and neck cancer. Head Neck. 2012;34: 245-59.

  10. Campbell AC, Gliech LL, Barrett WI, Gluckman JL. Cancerous seeding of the tracheostomy site in patients with upper aerodigestive tract squamous cell carcinoma. OtoLaryngol Head Neck Surg. 1999;120: 601-3.

  11. Halfpenny W and Mcguk M. Stomal recurrence following temporary tracheostomy. J Larynol Otol. 2001;115(3): 202-4.

  12. Szyfter W, Kruk-Zagajewska A, Borucki L, Gawecki W, Milek P. Stomal recurrence after total laryngectomy. Otolaryngol Pol. 2006;60(2): 149-55.

  13. Wang ZY, Li ZQ, Ji H, Chen W, Wu KM, Zhu MH, et al. Influence of risk factors on stomal recurrence after total laryngectomy for laryngeal carcinoma. A met-analysis. J Can Res. 2017;13: 856-61.

  14. Liang Y, Zhu X, Zeng W. Yu T, Fang F, Zhao Y. Which risk factors are associated with stomal recurrence after total laryngectomy for laryngeal cancer? Meta-analysis of the last 30 years. Braz J Oto Rhino Laryngol. 2020;86(4): 502-12.

  15. Yotakis J, Davris S, Kontozoglou T, Adamopoloos G. Evaluation of risk factors for stomal recurrence after total laryngectomy. Clin Otolaryngol & amp Allied Sci banner. 1996;21(2): 135-8.

  16. Varghese L, Mathew J, John S, Job A. Treatment of advanced carcinoma of the larynx and hypopharynx with laser followed by external Radiotherapy. Iran J Otolaryngol. 2017;29(94): 247-53.

  17. Petrovic Z, Djondjevic V. Stomal recurrence after primary total laryngectomy. Clin Otolaryngol Allies Sci. 2004;29(3): 270-3.

  18. Zhao H, Ren J, Zhuo X, Ye H, Zou J, Liu S. Stomal recurrence after total laryngectomy: a clinicopathological multivariante analysis. Am J Clin Oncol. 2009; 32(2): 154-7.

  19. Wong RJ, Shah JP. The role of head and neck surgeon in contemporary Multidisciplinary treatment programs for advanced head and neck cancer. Curr Open Otolaryngol Head Neck Surg. 2010;18: 79-82.

  20. Chu PY, Lee TL, Chang SY. Impact and management of airway obstruction in patients with squamous cell carcinoma of the larynx. Head Neck. 2011;33: 98-102.

  21. Ellies M, Steiner W. Peri and postoperative complications after laser surgery of tumor of the aerodigestive tract. Am J Otolaryngol. 2007;28: 168-172.

  22. Hinni MI, Salassa JR, Grant DJ, Pearson BW, Hayden RE, Martin A, et al. Transoral laser microsurgery for advanced laryngeal carcinoma. Arch Otolaryngol Head Neck Surg. 2007;133: 1198-1204.

  23. Du E, Smith RV, Ow JT, Tassler AB, Schiff BA. Tumor debulking in management of laryngeal cancer airway obstruction. Otolaryngol Head Neck Surg July. 2016;155: 805-807.

  24. Ohri N, Rapkin BD, Guha D, Haynes-lewis H, Guha C, Kalniki S, et al. Predictors of radiation therapy noncompliance in Urban academic cancer center. Int J Radiat Oncol Biol Phys. 2015;91: 232-238.




Read 1901 times Last modified on Wednesday, 14 July 2021 09:45

About AMH

Annals of Medicine & Health (AMH) is a peer reviewed medical journal that established and published by a governmental medical faculty titled Thamar University Faculty of Medicine & Health Sciences (TUFMHS). 


Faculty of Medicine & Health Sciences AL-Mohafadhah St. Dhamar City - Yemen

P.O.Box: 87246

Tel Fax: +967 6 509 578

Tel No: +967 6 509 577


Copyright © 2019 Thamar University - Faculty of Medicine and Health Sciences - Annals of Medicine & Health . All Rights Reserved. | Developed By ProSite Yemen